Pane zvinhu zvinoverengeka zviri kumavambo kweiyo obesidad. Pakati pezvakanyanya kukosha, isu pasina mubvunzo tinowana metabolic zvinhu uye maseru zvinhu. Kufutisa chirwere chisingaperi chinoonekwa nemafuta akawandisa uye ichozve chinoshandurwa kuita a kurema kuwedzera.
Nguva pfupi yapfuura nzira iyo vamwe shanduko metabolic ivo vanogona kuve nesimba pane kukura kwekuneta.
Iko kusarudzika kusarudzika kwe substrates nesimba kune iyo synthesis uye kuchengetedza kwe triglycerides.
Kuwedzera kushanda mukudzikisira kwe makabhohaidhiretsi, fatty acids uye amino acids, uye mukuchengetedza simba rekuwedzera muchimiro che triglycerides mune adipose tishu.
Kugonesa kwepamusoro kuita iyo basa zvepanyama, panodiwa simba shoma uye kwakawanda kwaro kunoshandurwa kuita triglycerides inochengetwa munyama yemafuta.
Kuvhiringidza panguva yekuunganidza iyo simba yakachengetwa se triglycerides mune adipose tishu.
ari masero mafuta izvo zvine hombe yepakati lipid droplet yakakomberedzwa neyakaonda muganhu we cytoplasm. Adipocytes anochengeta mafuta muhuwandu hwakaenzana ne80% kana 95% yehuwandu hwavo.
El tishu adipose inova yakakura kana saizi yemasero aripo ichiwedzera, ichiwedzera lipid kana kuwedzera huwandu hwesero. Kurera huremu kunogona kuve mugumisiro we hypertrophy, hyperplasia, kana zvese zviri zviviri.
ari mafuta anoisa dzinogona kuwedzerwa kusvika ku1000 nguva ne hypertrophy, maitiro anoitika chero nguva, chero bedzi maadipocyte aine saiti yakakwana. Iyo hyperplasia zvinoitika kunyanya sechikamu chekukura panguva yehucheche uye kuyaruka, asi zvakare mukukura kana mafuta emukati memasero aripo asvika pamuganhu weavo kugona.
Kana huremu hwakaderera, saizi yeiyo adiposis inoderera. Kuwanda kwemasero hakuwedzeri kudzamara hukuru hukuru hweaya hwasvika. Izvo zvakare haina kuderera nehuremu hwekudzora. Kudzivirira kunotora danho kubvira kamwe iyo mafuta uye zvinoramba zviripo, zvakaoma kuirasa.